Lab Member

Huifang Chen, M.S.

陈慧芳

Position：

Technician

Email：

chenhuifang@sjtu.edu.cn

Education:

2018-2021 Shanghai Jiao Tong University, M.S.      

2013-2018 Fujian Medical University, B.S.

Research Interest:

Biological information analysis of epigenetic modification of RNA in tumor microenvironment.

Publication:

  1. Chen H*,Yao J*, Bao R, Dong Y, Zhang T, Du Y, Wang G, Ni D, Xun Z, Niu X, Ye Y, Li HB. Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer. Mol Cancer. 2021 Feb 8;20(1):29.

  2. Ting Zhang1,2,3†, Chenbo Ding1,2*†, Huifang Chen1,2†, Jun Zhao4, Zhejun Chen1, Baiwen Chen1, Kaiqiong Mao1,2, Yajuan Hao1,2, Manolis Roulis5, Hao Xu5, Yuval Kluger4, Qiang Zou1, Youqiong Ye1, Meixiao Zhan6*, Richard A. Flavell5,7*, Hua-Bing Li1,2,5*. m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κb-mediated anti-apoptotic pathway.  Science Advances.

  3. Zhen Liu, Youqiong Ye, yizhe Liu, Yanfang Liu, Huifang Chen, Mengting Shen, Zhen Wang, Shenglin Huang, Leng Han, Zhiao Chen, and Xianghuo He. RNA helicase DHX37 facilitates liver cancer progression by cooperating with PLRG1 to drive super enhancer-mediated transcription of cyclin D1. Cancer Research.

  4. BAO Ru-juan, CHEN Hui-fang, DONG Yu, YE You-qiong, SU Bing. Construction of prognostic risk score model of colorectal cancer gene signature based on transcriptome dysregulation[J]. JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE).

  5. Ye Y, Kuang X, Xie Z, Liang L, Zhang Z, Zhang Y, Ma F, Gao Q, Chang R, Lee HH, Zhao S, Su J, Li H, Peng J, Chen H, Yin M, Peng C, Yang N, Wang J, Liu J, Liu H, Han L, Chen X. Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1. Genome Med. 2020 Sep 28;12(1):83.