Lab Member
Jian Gao, Ph.D.
高健
Position:
Associate Professor
Email:
gaojian8977@gmail.com
Education:
2016-2021 Tongji University, Ph.D.
2012-2016 Tongji University, B.S.
Post-Doctor：
2021-2023 Fudan University
Research Interest:
Computational Biology in Spatial Tumor Microenvironment and Cancer Immunity
Publication:
Jian Gao#, Qiming Wang#, Fangqiu Fu#, Yue Zhao#, Teng Yang#, Xiangze Li, Yihua Sun, Hong Hu , Longfei Ma, Longsheng Miao, Xiaoyang Luo , Ting Ye, Yiliang Zhang , Yang Zhang , Ziling Huang, Hang Li, Longlong Shao, Midie Xu, Kuaile Zhao, Shiyue Zhang, Mou Zhang, Jun Wang, Chong Dai, Xiaoxiao Shang, Tingyi An, Yawei Zhang, Jiaqing Xiang, Zhiwei Cao*, Bin Li* and Haiquan Chen*. Comprehensive Genomic and Transcriptomic Analyses Reveal Prognostic Stratification for Esophageal Squamous Cell Carcinoma. Signal Transduction and Targeted Therapy. 2025.
Chen H#*, Deng C#*, Gao J#, Wang J#, Fu F#, Wang Y#, Wang Q, Zhang M, Zhang S, Fan F, Liu K, Yang B, He Q, Zheng Q, Shen X, Wang J, Hu T, Zhu C, Yang F, He Y, Hu H, Wang J*, Li Y*, Zhang Y*, Cao Z*. Integrative spatial analysis reveals tumor heterogeneity and immune colony niche related to clinical outcomes in small cell lung cancer. Cancer Cell. 2025.
Gao J#, Mo S#, Wang J, Zhang M, Shi Y, Zhu C, Shang Y, Tang X, Zhang S, Wu X, Xu X, Wang Y, Li Z, Zheng G, Chen Z, Wang Q, Tang K*, Cao Z*. MACC: a visual interactive knowledgebase of metabolite-associated cell communications. Nucleic Acids Research. 2024.
Yue Zhao#, Jian Gao#, Jun Wang#, Fanfan Fan#, Chao Cheng, Danwen Qian, Ran Guo, Yang Zhang, Ting Ye, Marcellus Augustine, Yicong Lin, Jun Shang, Hang Li, Yunjian Pan, Qingyuan Huang, Haiqing Chen, Han Han, Zhendong Gao, Qiming Wang, Shiyue Zhang, Mou Zhang, Fangqiu Fu, Yueren Yan, Shanila Patel, Roberto Vendramin, Hui Yuan, Yawei Zhang, Jiaqing Xiang, Hong Hu, Yihua Sun, Yuan Li, Kevin Litchfield*, Zhiwei Cao* and Haiquan Chen*. Nature Communications. 2024.
Fan F#, Gao J#, Zhao Y#, Wang J#, Meng L, Ma J, Li T, Han H, Lai J, Gao Z, Li X, Guo R, Cao Z, Zhang Y*, Zhang X*, Chen H*. Elevated Mast Cell Abundance Is Associated with Enrichment of CCR2+ Cytotoxic T Cells and Favorable Prognosis in Lung Adenocarcinoma. Cancer Research. 2023.
Fan F#, Wang J#, Ma J#, Zhang S#, Gao J#, Gao Z*, Zhang X*, Chen H*. Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18. Nature Communications. 2025.
Gao, Jian#; Yin, Zuojing#; Wu, Zhuanbin#; Sheng, Zhen; Ma, Chao; Chen, Rui; Zhang, Xiongwen; Tang, Kailin; Fei, Jian*; Cao, Zhiwei* ; Probing Synergistic Targets by Natural Compounds for Hepatocellular Carcinoma, Frontiers in Cell and Developmental Biology. 2021.
Jian Gao#; Qiming Wang; Yuwei Huang; Kailin Tang; Xue Yang*; Zhiwei Cao* ; In Silico Study of Anti-Insomnia Mechanism for Suanzaoren Prescription, Frontiers in Pharmacology. 2019.
Yue Zhao#; Jun Shang#; Jian Gao#; Han Han; Zhendong Gao; Yueren Yan; Qiang Zheng; Ting Ye; Fangqiu Fu; Chaoqiang Deng; Zelin Ma; Yang Zhang; Difan Zheng; Shanbo Zheng; Yuan Li; Zhiwei Cao*; Leming Shi;* Haiquan Chen* ; Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma, Frontiers in Immunology. 2022.
Zikun Chen; Deyu Yan; Mou Zhang; Wenhao Han; Yuan Wang; Shudi Xu; Kailin Tang; Jian Gao*; Zhiwei Cao*; MetNC: Predicting Metabolites in vivo for Natural Compounds, Frontiers in Chemistry. 2022.
Deyu Yan#; Genhui Zheng#; Caicui Wang; Zikun Chen; Tiantian Mao; Jian Gao; Yu Yan; Xiangyi Chen; Xuejie Ji; Jinyu Yu; Saifeng Mo; Haonan Wen; Wenhao Han; Mengdi Zhou; Yuan Wang; Jun Wang; Kailin Tang*; Zhiwei Cao*; HIT 2.0: an enhanced platform for Herbal Ingredients’ Targets, Nucleic Acids Research. 2021.
Nan Y, Xing X, ShiyiWang, Tang Z, Felder FN, Zhang S, Ledda RE, Ding X, Yu R, Liu W, Shi F, Sun T, Cao Z, Zhang M, Gu Y, Zhang H, Gao J, Wang P, Tang W, Yu P, Kang H, Chen J, Lu X, Zhang B, Mamalakis M, Prinzi F, Carlini G, Cuneo L, Banerjee A, Xing Z, Zhu L, Mesbah Z, Jain D, Mayet T, Yuan H, Lyu Q, Qayyum A, Mazher M, Wells A, Walsh SL, Yang G. Hunting imaging biomarkers in pulmonary fibrosis: Benchmarks of the AIIB23 challenge. Medical Image Analysis. 2024.
Funding:
2025年国家自然科学基金青年项目，主持。
2023年上海市市级科技重大专项“国际人类表型组计划（二期）”，药靶发现子项目，研究骨干。
2022年上海市超级博士后计划第二档资助（博士后日常经费资助）。
2021年上海市浦东新区“海博计划”资助。