Education:

2024    Shanghai Jiaotong University              Ph.D.

2021      Shanghai Jiaotong University                M.S.

2018      Shanghai Jiaotong University                B.S.

Research interest:

The roles of RNA modification in tumor immunity

Publication:

1.     Ao Liu#, Yi Gao#, Qi Wang, Wenhao Lin, Zhiyang Ma, Xiaoqun Yang*, Lu Chen*, Danfeng Xu*. The heterogeneity and clonal evolution analysis of the advanced prostate cancer with castration resistance. J Transl Med. 2023 Sep;21(1):641. (#co-first author, * co-corresponding)

2.     Ao Liu#, Yi Gao#, Hai Huang#, Xiaoqun Yang, Wenhao Lin, Lu Chen*, Danfeng Xu*. A Combined Technology to Protect the Anatomic Integrity of Distal Urethral Sphincter Complex in Radical Prostatectomy Improves Early Urinary Continence Recovery Without Sacrifice of Oncological Outcomes. Front Oncol, 2021 Aug; 5:11:711093. (#co-first author，* co-corresponding)

3.     Ao Liu#, Miao Zhang#, Hai Huang#, Chuanjie Zhang, Xiaohao Ruan, Wenhao Lin, Biao Li, Lu Chen*, Danfeng Xu*. Clinical Utility of 18F-PSMA-1007 Positron Emission Tomography/Magnetic Resonance Imaging in Prostate Cancer: A Single-Center Experience. Front Oncol, 2021 Feb 11:10:612701. (#co-first author，*co-corresponding)

4.     Ao Liu#, Lu Chen#, Miao Zhang#, Hai Huang, Chuanjie Zhang, Xiaohao Ruan, Wenhao Lin, Biao Li*, Danfeng Xu*. Impact of PSMA PET on management of biochemical recurrent prostate cancer: a systematic review and meta-analysis of prospective studies. Clinical and Translational Imaging. 2021 Jan; 9: 95-108. (#co-first author，*co-corresponding)

5.     Hai Huang #, Ao Liu #, Yiming Liang #, Yaqun Xin #, Jiacheng Liu, Yining Hao, Da Huang, Lu Chen, Wei Li , Guangliang Jiang , Yuhua Huang , Yaoting Xu, Jie Zhang, Tonghui Ma*, Danfeng Xu*, Yi Gao*. A urinary assay for mutation and methylation biomarkers in the diagnosis and recurrence prediction of non-muscle invasive bladder cancer patients. BMC Med. 2023 Sep 19;21(1):357. (#co-first author，*co-corresponding)

6.     Qin Zhang#, Hai Huang#, Ao Liu#, Jiang Li, Chunying Liu, Bin Sun, Lu Chen, Yi Gao*, Danfeng Xu*, Changqing Su*. Cell division cycle 20 (CDC20) drives prostate cancer progression via stabilization of β-catenin in cancer stem-like cells. EBioMedicine, 2019 Apr;42:397-407. (#co-first author，*co-corresponding)

7.     Hai Huang#, Yi Gao#, Ao Liu#, Xiaoqun Yang, Fang Huang, Le Xu, Danfeng Xu*, Lu Chen*. EIF3D promotes sunitinib resistance of renal cell carcinoma by interacting with GRP78 and inhibiting its degradation. EBioMedicine, 2019 Nov;49:189-201. (#co-first author，*co-corresponding)

8.     Liu Yihan#, Wang Xiaojing#, Liu Ao#, Zhang Chuanjie, Wang Haofei, Shen Yan*, He Hongchao*. SIRT5 functions as a tumor suppressor in renal cell carcinoma by reversing the Warburg effect. J Transl Med. 2021 Dec 20;19(1):521. (#co-first author，*co-corresponding)

9.     ChuanJie Zhang#, Lu Chen#, WeiJuan Lou#, JunHui Su, JingYi Huang, Ao Liu, Yang Xu, HongChao He, Yi Gao*, DanFeng Xu*, Qingquan Li*. Aberrant activation of m6A demethylase FTO renders HIF2α(low/-) clear cell renal cell carcinoma sensitive to BRD9 inhibitors. Sci Transl Med, 2021 Sep 29; 13(613), eabf6045. (#co-first author，*co-corresponding)

10.  Ning Zhang#, Da Huang#, Guangliang Jiang, Siteng Chen, Xiaohao Ruan, Haitao Chen, Jingyi Huang, Ao Liu, Wenhui Zhang, Xiaoling Lin, Yishuo Wu, Qin Zhang, Jing Li, James Hok-Leung Tsu*, Gong-Hong Wei*, Rong Na*. Genome-Wide 3'-UTR Single Nucleotide Polymorphism Association Study Identifies Significant Prostate Cancer Risk-Associated Functional Loci at 8p21.2 in Chinese Population. Adv Sci (Weinh), 2022 Aug; 9(23), e2201420. (#co-first author，*co-corresponding)

11.  Chuanjie Zhang#, Li Chen#, Yihan Liu, Jingyi Huang, Ao Liu, Yang Xu, Yan Shen, Hongchao He*, Danfeng Xu*. Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma. Theranostics, 2021 Jan 11(8), 3676-3693. (#co-first author，*co-corresponding)

12.  Chuanjie Zhang#, Tianhe Chen#, Zongtai Li#, Ao Liu, Yang Xu, Yi Gao*, Danfeng Xu*. Depiction of tumor stemlike features and underlying relationships with hazard immune infiltrations based on large prostate cancer cohorts. Brief Bioinform, 2021 May 22(3). (#co-first author，*co-corresponding)

13.  Chuanjie Zhang#, Hongchao He#, Xin Hu#, Ao Liu, Da Huang, Yang Xu, Lu Chen*, Danfeng Xu*. Development and validation of a metastasis-associated prognostic signature based on single-cell RNA-seq in clear cell renal cell carcinoma. Aging (Albany NY), 2019 Nov 11(22), 10183-10202. (#co-first author，*co-corresponding)

14.  Siwei Xing, Ao Liu, Xiaoqun Yang, Lu Chen, Danfeng Xu. Tubulocystic renal cell carcinoma: Two-case report and literature review. Int J Immunopathol Pharmacol, 2021 Jan-Dec:35:20587384211002966.