Education:

2023    University of Science and Technology of China            Ph.D.

2016    Northwest A&F University                            B.S.

Research interest:

The roles of RNA modification in regulating homeostasis and function of T cells.  

Publication:

1.     Qielan Wu*, Shiyu Bai*, Miya Su, Yuwei Zhang, Xuran Chen, Ting Yue, Linfeng Xu, Lu Wang, Di Xie, Shuhang Li, Xiang Li, Sicheng Fu, Lili Wang, Chenxi Tian, Jun Pan, Yuanyuan Huang, Yuting Cai, Yu Wang, Fang Hu, Fengyin Li, Huimin Zhang# and Li Bai#. HIVEP3 inhibits fate decision of CD8+ iNKT cells after positive selection[J]. Journal of leukocyte biology, 2023, 114(4):335-346. (*co-first, #co-corresponding)

2.     Shiyu Bai*, Qielan Wu*, Shasha Zhu, Yuwei Zhang, Xuran Chen, Miya Su, Jun Pan, Shuhang Li, Ting Yue, Linfeng Xu, Di Xie, Chenxi Tian, Dan Zhao, Xiang Li, Junjie Hou, Lu Wang, Sicheng Fu, Yanhong Xue, Amin Jiang, Dong Li, Tao Xu, Zhigang Tian, Rongbin Zhou, Huimin Zhang# and Li Bai#. Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways[J]. Frontiers in Immunology, 2023, 13:1051045. (*co-first, #co-corresponding)

3.     Lili Wang*, Qielan Wu*,Jiwei Liu, Huimin Zhang# and Li Bai#. Lactic acid inhibits iNKT cell functions via a phosphodiesterase-5 dependent pathway[J]. Biochemical and Biophysical Research Communications, 2021, 547:9-14. (*co-first, #co-corresponding)

4.     Muziying Liu*, Ziqiang Yang*, Qielan Wu*, Yunru Yang, Dan Zhao, Qingyu Cheng, Yajuan Li, Gengyuan Liu, Changfeng Zhao, Jun Pan, Yuwei Zhang, Fang Deng# and Tengchuan Jin#. IL-4-secreting CD40L+ MAIT cells support antibody production in the peripheral blood of Heonch-Schönlein purpura patients[J]. Inflammation Research, 2024, 73: 35-46. (*co-first, #co-corresponding)

5.     Lu Wang, Zhilan Liu, Lili Wang, Qielan Wu, Xiang Li, Di Xie, Huimin Zhang, Yongdeng Zhang, Lusheng Gu, Yanhong Xue, Ting Yue, Gang Liu, Wei Ji, Haiming Wei, Tao Xu, and Li Bai. Spatial distribution of IL4 controls iNKT cell-DC crosstalk in tumors [J]. Cell Mol Immunol, 2020, 17(5): 496-506.

6.     Sicheng Fu, Kaixin He, Chenxi Tian, Hua Sun, Chenwen Zhu, Shiyu Bai, Jiwei Liu, Qielan Wu, Di Xie, Ting Yue, Zhuxia Shen, Qingqing Dai, Xiaojun Yu, Shu Zhu, Gang Liu, Rongbin Zhou, Shengzhong Duan, Zhigang Tian, Tao Xu, Hua Wang, and Li Bai. Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells [J]. Nat Commun, 2020, 11(1): 438.

7.     Shuhang Li, Linlin Wang, Zhihao Xu, Yuanyuan Huang, Rufeng Xue, Ting Yue, Linfeng Xu, Fanwu Gong, Shiyu Bai, Qielan Wu, Jiwei Liu, Bolong Lin, Huimin Zhang, Yanhong Xue, Pingyong Xu, Junjie Hou, Xiaofei Yang, Tengchuan Jin, Rongbin Zhou, Jizhong Lou, Tao Xu, and Li Bai. ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation [J]. J Exp Med, 2021, 218(9).

8.     Huimin Zhang, Yuwei Zhang, Jun Pan, Qielan Wu, Yuanyuan Huang, Shiyu Bai, Chenxi Tian, Mingzhao Zhu, Zhexiong Lian, Fengyin Li, Zhigang Tian, and Li Bai. iNKT subsets differ in their developmental and functional requirements on Foxo1 [J]. Proc Natl Acad Sci U S A, 2021, 118(46).

9.     Xiang Li, Chen Jin, Qi Chen, Xihua Zheng, Di Xie, Qielan Wu, Lu Wang, Shiyu Bai,  Huimin Zhang, and Li Bai. Identification of liver-specific CD24(+) invariant NK T cells with low granzyme B production and high proliferative capacity [J]. J Leukoc Biol, 2022, 111(6): 1199-210.