Tian Zhao, Ph.D.

赵田

Position：

Postdoctoral Fellow (2023)

Email：

zhaotian@shsmu.edu.cn

Education:

2023    Nankai University         Ph.D.

2015    Nankai University                     B.S.

Research Interest:

The roles of RNA modification in regulating mitochondrial homeostasis and ageing.

Publication:

1.     Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y. NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity. EMBO J. 2023 Aug 15;42(16):e113258.

2.     Chen L, Zhang Q, Meng Y, Zhao T, Mu C, Fu C, Deng C, Feng J, Du S, Liu W, Geng G, Ma K, Cheng H, Liu Q, Luo Q, Zhang J, Du Z, Cao L, Wang H, Liu Y, Lin J, Chen G, Liu L, Lam SM, Shui G, Zhu Y, Chen Q. Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function. EMBO Rep. 2023 Apr 5;24(4):e54731.

3.     Luo Q, Liu Q, Cheng H, Wang J, Zhao T, Zhang J, Mu C, Meng Y, Chen L, Zhou C, Lei H, Yang J, Chen G, Li Y, Pan L, Chen Q, Zhu Y. Nondegradable ubiquitinated ATG9A organizes Golgi integrity and dynamics upon stresses. Cell Rep. 2022 Aug 16;40(7):111195.

4.     Ma K, Zhang Z, Chang R, Cheng H, Mu C, Zhao T, Chen L, Zhang C, Luo Q, Lin J, Zhu Y, Chen Q. Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate. Cell Death Differ. 2020 Mar;27(3):1036-1051.

5.     Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, Ma K, Chang R, Liu Q, Gao R, Nie J, Xie J, Han J, Chen L, Ma G, Zhu Y, Chen Q. The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Nat Commun. 2019 Mar 4;10(1):1034.