Education:

2020-2024       Southeast University                              Ph.D.

2015-2018       Zhejiang Ocean University                   M.S.

2011-2015        Nanjing University of Information Science

  &Technology Bingjiang College            B.S

Research interest:

Bioinformatics and Epigenetics.

Publication:

1.     Siyan Meng#, Xiaoxu Liu#, Shiqi Zhu#, Peng Xie#, Haitong Fang, Qingyun Pan, Ke Fang, Fanfan Li, Jin Zhang, Zhuanzhuan Che, Quanyong Zhang, Guangyao Mao, Yan Wang, Ping Hu, Kai Chen, Fei Sun, Wei Xie, Zhuojuan Luo* & Chengqi Lin*, Young LINE-1 transposon 5’UTRs marked by elongation factor ELL3 function as enhancers to regulate naïve pluripotency in embryonic stem cells. Nature Cell Biology, 2023 Aug 17. (# co-first author, * co-corresponding, Cover story)

2.     Xiru Zhao#, Ke Fang#, Xiaoxu Liu#, Ruihuan Yao, Min Wang, Fanfan Li, Shaohua Hao, Jingjing He, Yan Wang, Menghan Fan, Wei Huang, Yiping Li, Chun Gao, Chengqi Lin*, Zhuojuan Luo*. QSER1 preserves the suppressive status of the pro-apoptotic genes to prevent apoptosis. Cell Death Differ. 2023 Mar;30(3):779-793. (# co-first author, * co-corresponding)

3.     Zhuanzhuan Che#, Xiaoxu Liu#, Qian Dai#, Ke Fang, Chenghao Guo, Junjie Yue, Haitong Fang, Peng Xie, Zhuojuan Luo*, Chengqi Lin*. Distinct roles of the two SEC scaffold proteins, AFF1 and AFF4, in regulating RNA Pol II transcription elongation. J Mol Cell Biol. 2023 Aug 1. (# co-first author, * co-corresponding)

4.     Yan Wang, Binbin Ma, Xiaoxu Liu, Ge Gao, Zhuanzhuan Che, Menghan Fan, Siyan Meng, Xiru Zhao, Rio Sugimura, Hua Cao, Zhongjun Zhou, Jing Xie, Chengqi Lin*, Zhuojuan Luo*. ZFP281-BRCA2 prevents R-loop accumulation during DNA replication. Nat Commun. 2022 Jun 17;13(1):3493. (* co-corresponding)

5.     Junjie Yue#, Qian Dai#, Shaohua Hao, Shiqi Zhu, Xiaoxu Liu, Zhiqun Tang, Meng Li, Haitong Fang, Chengqi Lin*, Zhuojuan Luo*. Suppression of the NTS-CPS1 regulatory axis by AFF1 in lung adenocarcinoma cells. J Biol Chem. 2021 Jan-Jun;296:100319. (# co-first author, * co-corresponding)

6.     Hao Du#, Chen Chen#, Yan Wang, Yang Yang, Zhuanzhuan Che, Xiaoxu Liu, Siyan Meng, Chenghao Guo, Manman Xu, Haitong Fang, Fengchao Wang, Chengqi Lin*, Zhuojuan Luo*. RNF219 interacts with CCR4-NOT in regulating stem cell differentiation. J Mol Cell Biol. 2020 Oct 26;12(11):894-905. (# co-first author, * co-corresponding)

7.     Zhuojuan Luo#, Xiaoxu Liu#, Hao Xie#, Yan Wang, Chengqi Lin*. ZFP281 Recruits MYC to Active Promoters in Regulating Transcriptional Initiation and Elongation. Mol Cell Biol. 2019 Nov 25;39(24):e00329-19. (# co-first author, * co-corresponding)

8.     Yue Zhang, Chao Wang, Xiaoxu Liu, Qian Yang, Hongliang Ji, Mengjun Yang, Manman Xu, Yunyan Zhou, Wei Xie, Zhuojuan Luo*, Chengqi Lin*. AFF3-DNA methylation interplay in maintaining the mono-allelic expression pattern of XIST in terminally differentiated cells. J Mol Cell Biol. 2019 Sep 19;11(9):761-769. (* co-corresponding)

9.     Xiaoxu Liu, Weiye Li, Lihua Jiang*, Zhenming Lü, Minhai Liu, Li Gong, Bingjian Liu, Liqin Liu, Xiaolong Yin. Immunity-associated long non-coding RNA and expression in response to bacterial infection in large yellow croaker (Larimichthys crocea). Fish Shellfish Immunol. 2019 Nov;94:634-642. (* co-corresponding)

10.  Wei Liu#, Xiaoxu Liu#, Changwen Wu*, Lihua Jiang*. Transcriptome analysis demonstrates that long noncoding RNA is involved in the hypoxic response in Larimichthys crocea. Fish Physiol Biochem. 2018 Oct;44(5):1333-1347. (# co-first author, * co-corresponding)

11.  Xiaoxu Liu, Lisen Kang, Wei Liu, Bao Lou, Changwen Wu*, Lihua Jiang*. Molecular characterization and expression analysis of the large yellow croaker (Larimichthys crocea) chemokine receptors CXCR2, CXCR3, and CXCR4 after bacterial and poly I:C challenge. Fish Shellfish Immunol. 2017 Nov;70:228-239. (* co-corresponding)

12.  Xiaoxu Liu, Lisen Kang, MeiYing Xu, Changwen Wu*, Lihua Jiang*. Phylogenetic estimation of Mytilidae in the East China Sea inferred from mitochondrial genes and nuclear DNA sequence variation. Biochemical Systematics and Ecology. 71(2017):219-224. (* co-corresponding)