Lab Member
Xiaxia Han
韩霞霞
Position:
PhD Student (2025)
Email:
hanxiaxiaxx@163.com
Education:
2025 Chongqing Medical University, Ph.D. Candidate
2022 Chongqing Medical University, M.D.
2012 Southwest Minzu University, B.E.
Research Interest:
The roles of RNA modification in regulating immune cells homeostasis and function.
Publication:
Shen MY, Hao YN, Han X , Wang BZ, Li L, Chen T, Chen SY, Zou L, Huang JJ, Wang W, Liu SC, Han XJ, Jin AS*. Therapeutic potential of T - cell receptor targeting the HLA - A*11:01 - restricted KRAS^G12V neoantigen without cross - recognition of the self - antigen RAB7B in solid tumors. J Immunother Cancer, 2025, 13 (7): e011863.
Han X#, Han X#, Mu S, Li Y, Li L, Wang Y, Li S, Li T, Shen M*, Jin A*. Identification of novel KRASⁿᵉᵒᵃⁿᵗⁱᵍᵉⁿ ˢᵖᵉᶜⁱᶠⁱᶜ TCRs and a strategy to eliminate off - target recognition. J Transl Med, 2025, 23(1): 78. (#co - firstAuthor, *corresponding Author ）
Junfan Wang#, Xiaojian Han, Yanan Hao, Siyin Chen, Bo Pang, Lin Zou, Xiaxia Han, Wang Wang, Li Liu, Meiying Shen, Aishun Jin*. Cbl - b inhibition promotes less differentiated phenotypes of T cells with enhanced cytokine production. Cell Immunol, 2024, 403 - 404: 104863.
Meiying Shen#, Siyin Chen#, Xiaojian Han, Yanan Hao, Junfan Wang, Luo Li, Tong Chen, Bozhi Wang, Lin Zou, Tong Zhang, Wanli Zhang, Xiaxia Han, Wang Wang, Haochen Yu, Kang Li, Shengchun Liu, Aishun Jin*. Identification of an HLA - A*11:01 - restricted neoepitope of mutant PIK3CA and its specific T cell receptors for cancer immunotherapy targeting hotspot driver mutations. Cancer Immunol Immunother, 2024, 73 (8): 150.