Lab Member

Xuefei Wang, Ph.D.

王雪飞

Position：

Assistant Professor (2023)

Postdoctoral Fellow (2019)

Email：

wangxf@shsmu.edu.cn

wangxf09sk@163.com

Education:

2019    Institute of Microbiology, Chinese Academy of Sciences (CAS), Ph.D.

2013    Inner Mongolia University, B.S.

Research Interest:

The roles of RNA epigenetics modification in tumor-associated macrophage and tumor immunity.

Publication:

  1. Wang, X.#, Chen, C.#, Sun, H.#, Mao, K.#, Yao, J.#, Zhang, W., Zhan, M., Li, H.B., Zhang, Z., Zhu, S., Lu, L. (2023). m6A mRNA modification potentiates Th17 functions to inflame autoimmunity. Sci China Life Sci 66, https://doi.org/10.1007/s11427-022-2323-4

  2. Liu Y#, Zhou J#, Li X#, Zhang X#, Shi J#, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zhen J, Liu RJ, Su B, Ye Y, Flavell RA*, Yi C*, Wu Y*, Li HB*. (2022) tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis. Nature Immunology, 2022 Oct;23. READ

  3. Jiyu Tong#; Xuefei Wang#; Yongbo Liu#; Xingxing Ren#; Anmin Wang; Zonggui Chen; Jiameng Yao; Kaiqiong Mao; Tingting Liu; Fei-Long Meng; Wen Pan; Qiang Zou; Jun Liu; Yu Zhou; Qiang Xia; Richard A. Flavell; Shu Zhu; Hua-Bing Li ; Pooled CRISPR screening identifies m(6)A as a positive regulator of macrophage activation, Science Advances, 2021, 7(18)

  4. Xuefei Wang; Jianling Yang; Guijie Guo; Riyue Feng; Ke Chen; Yuan Liao; Lianfeng Zhang; Liping Sun; Shile Huang; Ji-Long Chen*; Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway, Molecular cancer, 2019, 18: 84.

  5. Riyue Feng#; Xuefei Wang#; Jianning Li#; Ke Chen; Guijie Guo; Yuan Liao; Liping Sun; Shile Huang; Ji-Long Chen*; Interaction of Abl tyrosine kinases with SOCS3 impairs its suppressor function in tumorigenesis, Neoplasia, 2018, 20: 1095-1105.

  6. Xuefei Wang; Shile Huang; Ji-Long Chen*; Understanding of leukemic stem cells and their clinical implications, Molecular cancer, 2017, 16: 2.

  7. Xuefei Wang; Ke Chen; Guijie Guo; Ji-Long Chen*; Noncoding RNAs and their functional involvement in regulation of chronic myeloid leukemia, Briefings in functional genomics, 2016, 15: 239-248.

  8. Guijie Guo; Qingzheng Kang; Xiaomei Zhu; Qinghuang Chen; Xuefei Wang; Yuhai Chen; Jing Ouyang; Lianfeng Zhang; Huo Tan; Runsheng Chen; Shile Huang; and Ji-Long Chen*; A long noncoding RNA critically regulates Bcr-Abl-mediated cellular transformation by acting as a competitive endogenous RNA, Oncogene, 2015; 34:1768–1779.