Yongbo Liu, Ph.D.

刘永波

Position：

Associate Professor

Email：

liuyongbo@sibs.ac.cn

Education:

2018    University of Chinese Academy of Sciences, Ph.D.

2013    NORTHWEST A&F University, B.S.

Research Interest:

The roles of m1A tRNA methylation in immune cells development and homeostasis.

Publication:

1.     Jiyu Tong; Xuefei Wang; Yongbo Liu; Xingxing Ren; Anmin Wang; Zonggui Chen; Jiameng Yao; Kaiqiong Mao; Tingting Liu; Fei-Long Meng; Wen Pan; Qiang Zou; Jun Liu; Yu Zhou; Qiang Xia; Richard A. Flavell; Shu Zhu; Hua-Bing Li ; Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation, SCIENCE ADVANCES, 2021, 7(18)

2.     Liu Yongbo; Li Hua Bing; Flavell Richard A ; cGAS activation in phased droplets, Cell Research, 2018, 28(10): 967-968

3.     Yongbo Liu, Cunxian Fan, Yifan Zhang, Xianjun Yu, Xiaoxia Wu, Xixi Zhang, Qun Zhao, Haiwei Zhang, Qun Xie, Ming Li, Xiaoming Li, Qiurong Ding, Hao Ying, Dali Li and Haibing Zhang. RIP1 kinase activity-dependent roles in embryonic development of Fadd deficient mice. Cell Death and Differentiation advance online publication, 2 June 2017

4.     Qun Zhao, XianJun Yu, HaiWei Zhang, YongBo Liu, XiXi Zhang, XiaoXia Wu, Qun Xie, Ming Li, Hao Ying, and Haibing Zhang.RIPK3 Mediates Necroptosis during Embryonic Development and Postnatal Inflammation in Fadd-Deficient Mice. Cell Reports 19, 798–808, April 25, 2017

5.     Xianjun Yu, Qun Zhao, Xixi Zhang, Haiwei Zhang, Yongbo Liu, Xiaoxia Wu, Ming Li, Xiaoming Li, Jingxuan Zhang, Xuzhi Ruan and Haibing Zhang. Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation. Published: June 27, 2017

6.     Xixi Zhang, Cunxian Fan, Haiwei Zhang, Qun Zhao, Yongbo Liu, Chengxian Xu, Qun Xie, Xiaoxia Wu, Xianjun Yu, Jianke Zhang, Haibing Zhang. MLKL and FADD are Critical for Suppressing Progressive Lymphoaccumulative Disease and Activating NLRP3 Inflammasome. Cell Reports. 16, 1-13, online: August 4 , 2016

7.     Yu X, Zhao Q, Zhang H, Fan C, Zhang X, Xie Q, Xu C, Liu Y, Wu X, Han Q, Zhang H. Gambogenic acid inhibit s LPS-simulated inflammatory response by suppressing NF-κB and MAPK in macrophages. Act a Biochim Biophys Sin. 2016 May; 4 8(5): 4 54 -61

8.     Zhang HW, Zhang X, Fan C, Xie Q, Xu C, Qun Zhao, Liu Y, Wu X, Zhang H. A novel sgRNA selection system for CRISPR-Cas9 in mammalian cells. Biochem Biophys Res Commun. 2016 Mar 18;4 71(4 ):528-32